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Image Search Results
Journal: Bioscience Reports
Article Title: Identification of CCT3 as a prognostic factor and correlates with cell survival and invasion of head and neck squamous cell carcinoma
doi: 10.1042/BSR20211137
Figure Lengend Snippet: ( A ) CERES score was obtained from Depmap datasource and used to access the significance of CCT3 for cell survival of HNSCC. CERES score approach to -1 means the gene is important for cell survival, while score approach to 0 means the gene is not an essential gene. ( B ) SCC25 and CAL27 cells were transfected with control siRNA or siRNA-CCT3 for 48 h. Cells were harvested and subjected to Western blot assay to detect the expression of CCT3. A CCK-8 assay was performed to detect cell viability of SCC25 ( C ) and CAL27 ( D ) cells after being transfected with siRNA. ( E ) A wound healing assay was performed to determine the cell invasion of SCC25 and CAL27 cells after being transfected with siRNA. The cells were photographed at 0 or 48 h; *, P < 0.05; **, P < 0.01; ***, P < 0.001; CCT3, Chaperonin-containing TCP-1 3.
Article Snippet: The human tongue squamous cell carcinoma cell lines SCC25 and
Techniques: Transfection, Control, Western Blot, Expressing, CCK-8 Assay, Wound Healing Assay